Epistatic interactions modulate the evolution of mammalian mitochondrial respiratory complex components
<p>Abstract</p> <p>Background</p> <p>The deleterious effect of a mutation can be reverted by a second-site interacting residue. This is an epistatic compensatory process explaining why mutations that are deleterious in some species are tolerated in phylogenetically rela...
Main Authors: | Moleirinho Ana, van Asch Barbara, Carneiro João, Azevedo Luísa, Pereira Filipe, Amorim António |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2009-06-01
|
Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/10/266 |
Similar Items
-
Molecular evolution of mammalian genes with epistatic interactions in fertilization
by: Claire C. Morgan, et al.
Published: (2019-07-01) -
Epistatic adaptive evolution of human color vision.
by: Shozo Yokoyama, et al.
Published: (2014-12-01) -
The adaptive evolution of the mammalian mitochondrial genome
by: O'Brien Stephen J, et al.
Published: (2008-03-01) -
An epistatic explanation
by: Yoshihiro Komatsu, et al.
Published: (2016-09-01) -
Epistatically interacting substitutions are enriched during adaptive protein evolution.
by: Lizhi Ian Gong, et al.
Published: (2014-05-01)