Fgf8-related secondary organizers exert different polarizing planar instructions along the mouse anterior neural tube.

Early brain patterning depends on proper arrangement of positional information. This information is given by gradients of secreted signaling molecules (morphogens) detected by individual cells within the responding tissue, leading to specific fate decisions. Here we report that the morphogen FGF8 ex...

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Bibliographic Details
Main Authors: Ivan Crespo-Enriquez, Juha Partanen, Salvador Martinez, Diego Echevarria
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3391221?pdf=render