Stage 2 Registered Report: Variation in neurodevelopmental outcomes in children with sex chromosome trisomies: testing the double hit hypothesis [version 3; peer review: 2 approved]

Background: The presence of an extra sex chromosome is associated with an increased rate of neurodevelopmental difficulties involving language. The 'double hit' hypothesis proposes that the adverse impact of the extra sex chromosome is amplified when genes that are expressed from the sex c...

Full description

Bibliographic Details
Main Authors: Dianne F. Newbury, Nuala H. Simpson, Paul A. Thompson, Dorothy V. M. Bishop
Format: Article
Language:English
Published: Wellcome 2020-09-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/3-85/v3