Native Low-Density Lipoproteins Act in Synergy with Lipopolysaccharide to Alter the Balance of Human Monocyte Subsets and Their Ability to Produce IL-1 Beta, CCR2, and CX3CR1 In Vitro and In Vivo: Implications in Atherogenesis

Native Low-Density Lipoproteins Act in Synergy with Lipopolysaccharide to Alter the Balance of Human Monocyte Subsets and Their Ability to Produce IL-1 Beta, CCR2, and CX3CR1 In Vitro and In Vivo: Implications in Atherogenesis

Increasing evidence has demonstrated that oxidized low-density lipoproteins (oxLDL) and lipopolysaccharide (LPS) enhance accumulation of interleukin (IL)-1 beta-producing macrophages in atherosclerotic lesions. However, the potential synergistic effect of native LDL (nLDL) and LPS on the inflammator...

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Bibliographic Details
Main Authors: Aarón N. Manjarrez-Reyna, Camilo P. Martínez-Reyes, José A. Aguayo-Guerrero, Lucia A. Méndez-García, Marcela Esquivel-Velázquez, Sonia León-Cabrera, Gilberto Vargas-Alarcón, José M. Fragoso, Elizabeth Carreón-Torres, Oscar Pérez-Méndez, Jessica L. Prieto-Chávez, Galileo Escobedo
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomolecules
Subjects:
atherogenesis
monocyte subpopulations
native LDL
LPS
IL-1 beta
CCR2
Online Access:https://www.mdpi.com/2218-273X/11/8/1169

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https://www.mdpi.com/2218-273X/11/8/1169

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