6-Bromo-<i>N</i>-(2-methyl-2<i>H</i>-benzo[<i>d</i>][1,2,3]triazol-5-yl)quinolin-4-amine

6-Bromo-<i>N</i>-(2-methyl-2<i>H</i>-benzo[<i>d</i>][1,2,3]triazol-5-yl)quinolin-4-amine

We describe a straightforward synthesis of the title compound, incorporating a relatively rare 2-methyl-2<i>H</i>-1,2,3-triazole heterocylic motif as a potential kinase inhibitor motif. The small molecule crystal structure has been resolved, revealing an interesting packing arrangement a...

Full description

Bibliographic Details
Main Authors: Christopher R. M. Asquith, Graham J. Tizzard
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molbank
Subjects:
2-methyl-2<i>h</i>-1,2,3-triazole
4-anilino-quin(az)olines
conformational flexibility
hinge binder
kinase inhibitor design
Online Access:https://www.mdpi.com/1422-8599/2019/4/M1087

Internet

https://www.mdpi.com/1422-8599/2019/4/M1087

Similar Items