SIRT5 Inhibition Induces Brown Fat-Like Phenotype in 3T3-L1 Preadipocytes

SIRT5 Inhibition Induces Brown Fat-Like Phenotype in 3T3-L1 Preadipocytes

Brown adipose tissue (BAT) activity plays a key role in regulating systemic energy. The activation of BAT results in increased energy expenditure, making this tissue an attractive pharmacological target for therapies against obesity and type 2 diabetes. Sirtuin 5 (SIRT5) affects BAT function by regu...

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Bibliographic Details
Main Authors: Francesca Molinari, Alessandra Feraco, Simone Mirabilii, Serena Saladini, Luigi Sansone, Enza Vernucci, Giada Tomaselli, Vincenzo Marzolla, Dante Rotili, Matteo A. Russo, Maria Rosaria Ricciardi, Agostino Tafuri, Antonello Mai, Massimiliano Caprio, Marco Tafani, Andrea Armani
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
obesity
adipogenesis
mitochondrial function
adipose tissue
sirtuins
Online Access:https://www.mdpi.com/2073-4409/10/5/1126

Internet

https://www.mdpi.com/2073-4409/10/5/1126

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