Visualizing Human Colorectal Cancer Intratumor Heterogeneity with Phylogeography
Phylogeography combines ancestry with location and can be translated to intratumor heterogeneity (ITH) to visualize how tumors spread. ITH is common in human tumors, with many genetic and phenotypic differences between regions. The roles of ITH in progression are uncertain because many subclones lac...
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Format: | Article |
Language: | English |
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Elsevier
2020-07-01
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Series: | iScience |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004220304910 |