Nrf2 Suppression Delays Diabetic Wound Healing Through Sustained Oxidative Stress and Inflammation

Nrf2 Suppression Delays Diabetic Wound Healing Through Sustained Oxidative Stress and Inflammation

Impaired wound healing is one of the major complications of diabetes, involving prolonged inflammation, delayed re-epithelialization, and consistent oxidative stress. The detailed mechanism remains unclear, and there is currently no effective treatment for diabetic wound healing. In this study, we a...

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Bibliographic Details
Main Authors: Min Li, Haibing Yu, Haiyan Pan, Xueqing Zhou, Qiongfang Ruan, Danli Kong, Zhigang Chu, Huawen Li, Jingwen Huang, Xiaodong Huang, Angel Chau, Weiguo Xie, Yuanlin Ding, Paul Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
dimethyl fumarate
HO1
NQO1
Nrf2
wound healing
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01099/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01099/full

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