Heterologous biosynthesis and characterization of a glycocin from a thermophilic bacterium

Heterologous production of the glycocins, posttranslationally modified peptide bacteriocins containing a sugar moiety, has not been achieved. Here, the authors express a thermophilic bacterium glycocin biosynthetic gene cluster and S-glycosyltransferase for the production of antibacterial glycocins...

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Bibliographic Details
Main Authors: Arnoldas Kaunietis, Andrius Buivydas, Donaldas J. Čitavičius, Oscar P. Kuipers
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09065-5