Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells

Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells

Abstract Development of liver fibrosis results in drastic changes in the liver microenvironment, which in turn accelerates disease progression. Although the pathological function of various hepatic cells in fibrogenesis is identified, the crosstalk between them remains obscure. The present study dem...

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Bibliographic Details
Main Authors: Xiaoping Wu, Lingling Shu, Zixuan Zhang, Jingjing Li, Jiuyu Zong, Lai Yee Cheong, Dewei Ye, Karen S. L. Lam, Erfei Song, Cunchuan Wang, Aimin Xu, Ruby L. C. Hoo
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Advanced Science
Subjects:
A‐FABP
hepatic stellate cells
liver fibrosis
liver sinusoidal endothelial cells
TGFβ1
Online Access:https://doi.org/10.1002/advs.202003721

Internet

https://doi.org/10.1002/advs.202003721

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