Vascular α1A Adrenergic Receptors as a Potential Therapeutic Target for IPAD in Alzheimer’s Disease

Vascular α1A Adrenergic Receptors as a Potential Therapeutic Target for IPAD in Alzheimer’s Disease

Drainage of interstitial fluid from the brain occurs via the intramural periarterial drainage (IPAD) pathways along the basement membranes of cerebral capillaries and arteries against the direction of blood flow into the brain. The cerebrovascular smooth muscle cells (SMCs) provide the motive force...

Full description

Bibliographic Details
Main Authors: Miles Frost, Abby Keable, Dan Baseley, Amber Sealy, Diana Andreea Zbarcea, Maureen Gatherer, Ho Ming Yuen, Matt MacGregor Sharp, Roy O. Weller, Johannes Attems, Colin Smith, Paul R. Chiarot, Roxana O. Carare
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceuticals
Subjects:
α<sub>1A</sub> adrenergic receptor
intramural periarterial drainage
cerebral blood vessels
Online Access:https://www.mdpi.com/1424-8247/13/9/261

Internet

https://www.mdpi.com/1424-8247/13/9/261

Similar Items