Cucumarioside A2-2 Causes Macrophage Activation in Mouse Spleen

Cucumarioside A2-2 Causes Macrophage Activation in Mouse Spleen

The immunomodulatory effect of triterpene glycoside cucumarioside A2-2 (CA2-2), isolated from the Far Eastern sea cucumber Cucumaria japonica, was compared with lipopolysaccharide (LPS) on mouse spleen. It has been shown that the intraperitoneal (i.p.) glycoside administration leads to increased spl...

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Bibliographic Details
Main Authors: Evgeny A. Pislyagin, Igor V. Manzhulo, Tatiana Y. Gorpenchenko, Pavel S. Dmitrenok, Sergey A. Avilov, Alexandra S. Silchenko, Yun-Ming Wang, Dmitry L. Aminin
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Marine Drugs
Subjects:
immunomodulation
LPS
iba-1
IL-1β
NO
iNOs
ROS
sea cucumbers
spleen
triterpene glycosides
Online Access:https://www.mdpi.com/1660-3397/15/11/341

Internet

https://www.mdpi.com/1660-3397/15/11/341

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