Fms-like tyrosine kinase 3 ligand controls formation of regulatory T cells in autoimmune arthritis.

Fms-like tyrosine kinase 3 ligand controls formation of regulatory T cells in autoimmune arthritis.

Fms-like tyrosine kinase 3 ligand (Flt3L) is known as the primary differentiation and survival factor for dendritic cells (DCs). Furthermore, Flt3L is involved in the homeostatic feedback loop between DCs and regulatory T cell (Treg). We have previously shown that Flt3L accumulates in the synovial f...

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Bibliographic Details
Main Authors: Mattias N D Svensson, Sofia E M Andersson, Malin C Erlandsson, Ing-Marie Jonsson, Anna-Karin H Ekwall, Karin M E Andersson, Anders Nilsson, Li Bian, Mikael Brisslert, Maria I Bokarewa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3549988?pdf=render

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http://europepmc.org/articles/PMC3549988?pdf=render

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