Tau Pathology and Parietal White Matter Lesions Have Independent but Synergistic Effects on Early Development of Alzheimer's Disease

Background: White matter lesions (WMLs) are a common finding in patients with dementia. This study investigates the relationship between WMLs, hyperphosphorylated tau (P-tau) in cerebrospinal fluid (CSF) and apolipoprotein E (APOE) ε4 genotype in prodromal Alzheimer's disease (AD). Methods: Bas...

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Bibliographic Details
Main Authors: Joakim Hertze, Sebastian Palmqvist, Lennart Minthon, Oskar Hansson
Format: Article
Language:English
Published: Karger Publishers 2013-04-01
Series:Dementia and Geriatric Cognitive Disorders Extra
Subjects:
Online Access:http://www.karger.com/Article/FullText/348353