Autoantibodies against Protein Phosphatase Magnesium-Dependent 1A as a Biomarker for Predicting Radiographic Progression in Ankylosing Spondylitis Treated with Anti-Tumor Necrosis Factor Agents

Autoantibodies against Protein Phosphatase Magnesium-Dependent 1A as a Biomarker for Predicting Radiographic Progression in Ankylosing Spondylitis Treated with Anti-Tumor Necrosis Factor Agents

Background: Patients with ankylosing spondylitis (AS) have increased levels of protein phosphatase magnesium-dependent 1A (PPM1A) and autoantibodies. We evaluated the usefulness of serum anti-PPM1A antibodies as a biomarker for AS. Methods: Serum samples from 58 AS patients were obtained from a mult...

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Bibliographic Details
Main Authors: Jung-Sun Lee, Eun-Ju Lee, Jae-Hyun Lee, Seok-Chan Hong, Chang-Keun Lee, Bin Yoo, Ji-Seon Oh, Sang-Hoon Lee, Tae-Jong Kim, Seung-Hun Lee, Sung-Sin Jo, Dae-Hyun Yoo, Ye-Soo Park, Tae-Hwan Kim, Yong-Gil Kim
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Journal of Clinical Medicine
Subjects:
ankylosing spondylitis
autoantibody
biomarkers
protein phosphatase magnesium-dependent 1 A
radiographic progression
Online Access:https://www.mdpi.com/2077-0383/9/12/3968

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https://www.mdpi.com/2077-0383/9/12/3968

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