Ubc9 Attenuates Myocardial Ischemic Injury Through Accelerating Autophagic Flux

Ubc9 Attenuates Myocardial Ischemic Injury Through Accelerating Autophagic Flux

AimsSUMOylation is a post-translational modification that plays a crucial role in the cellular stress response. We aimed to demonstrate whether and how the SUMO E2 conjugation enzyme Ubc9 affects acute myocardial ischemic (MI) injury.Methods and ResultsAdenovirus expressing Ubc9 was administrated by...

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Bibliographic Details
Main Authors: Qing Xiao, Xiu-Hui Chen, Ru-Chao Jiang, Sheng-Ying Chen, Kai-Feng Chen, Xiang Zhu, Xiao-ling Zhang, Jun-jun Huang, Yuan Qin, Gui-Ping Zhang, Quan Yi, Jian-dong Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
Ubc9
SUMOylation
myocardial ischemia
autophagy
PI3K-Ⅲ complexes
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.561306/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.561306/full

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