<i>Bacteroides fragilis</i> Enterotoxin Induces Sulfiredoxin-1 Expression in Intestinal Epithelial Cell Lines Through a Mitogen-Activated Protein Kinases- and Nrf2-Dependent Pathway, Leading to the Suppression of Apoptosis

<i>Bacteroides fragilis</i> Enterotoxin Induces Sulfiredoxin-1 Expression in Intestinal Epithelial Cell Lines Through a Mitogen-Activated Protein Kinases- and Nrf2-Dependent Pathway, Leading to the Suppression of Apoptosis

Enterotoxigenic <i>Bacteroides fragilis</i> is a causative agent of colitis and secrets enterotoxin (BFT), leading to the disease. Sulfiredoxin (Srx)-1 serves to protect from oxidative damages. Although BFT can generate reactive oxygen species in intestinal epithelial cells (IECs), no Sr...

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Bibliographic Details
Main Authors: Jong Ik Jeon, Jun Ho Choi, Keun Hwa Lee, Jung Mogg Kim
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Bacteroides fragilis</i>
enterotoxin
intestinal epithelial cells
sulfiredoxin-1
Online Access:https://www.mdpi.com/1422-0067/21/15/5383

Internet

https://www.mdpi.com/1422-0067/21/15/5383

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