Amyloid Associated Intermittent Network Disruptions in Cognitively Intact Older Subjects: Structural Connectivity Matters

Amyloid Associated Intermittent Network Disruptions in Cognitively Intact Older Subjects: Structural Connectivity Matters

Observations in animal models suggest that amyloid can cause network hypersynchrony in the early preclinical phase of Alzheimer's disease (AD). The aim of this study was (a) to obtain evidence of paroxysmal hypersynchrony in cognitively intact subjects (CN) with increased brain amyloid load fro...

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Bibliographic Details
Main Authors: Susanne G. Mueller, Michael W. Weiner
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
amyloid
intermittent
functional connectivity
cognitively intact
hypersynchrony
resting state fMRI
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00418/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2017.00418/full

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