Discrete Element Framework for Modelling Extracellular Matrix, Deformable Cells and Subcellular Components.

Discrete Element Framework for Modelling Extracellular Matrix, Deformable Cells and Subcellular Components.

This paper presents a framework for modelling biological tissues based on discrete particles. Cell components (e.g. cell membranes, cell cytoskeleton, cell nucleus) and extracellular matrix (e.g. collagen) are represented using collections of particles. Simple particle to particle interaction laws a...

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Bibliographic Details
Main Authors: Bruce S Gardiner, Kelvin K L Wong, Grand R Joldes, Addison J Rich, Chin Wee Tan, Antony W Burgess, David W Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4599884?pdf=render

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http://europepmc.org/articles/PMC4599884?pdf=render

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