Synthesis and Characterization of Some New Coumarin Derivatives as Probable Breast Anticancer MCF-7 Drugs

Synthesis and Characterization of Some New Coumarin Derivatives as Probable Breast Anticancer MCF-7 Drugs

This study aimed to synthesize quinolinone derivatives and investigate their cytotoxic activity. The compound 1-azacoumarin-3-carboxylic acid (2-oxo-1H-quinoline-3-carboxylic acid) was obtained via the cyclocondensation of 2-hydroxybenzaldehyde with diethyl malonate in base catalyst to give ethyl co...

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Bibliographic Details
Main Authors: Ahmed Gaber, Walaa F. Alsanie, Majid Alhomrani, Abdulhakeem S. Alamri, Ibrahim M. El-Deen, Moamen S. Refat
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Crystals
Subjects:
anticancer drugs
quinolinone derivatives
MCF-7
cell cycle arrest
Online Access:https://www.mdpi.com/2073-4352/11/5/565

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https://www.mdpi.com/2073-4352/11/5/565

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