VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9

VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9

The method of delivery of CRISPR-Cas9 into target cells is a strong determinant of efficacy and specificity in genome editing. Even though high efficiency of Cas9 delivery is necessary for optimal editing, its long-term and high levels of expression correlate with increased off-target activity. We d...

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Bibliographic Details
Main Authors: Claudia Montagna, Gianluca Petris, Antonio Casini, Giulia Maule, Gian Marco Franceschini, Ilaria Zanella, Luciano Conti, Francesca Arnoldi, Oscar R. Burrone, Lorena Zentilin, Serena Zacchigna, Mauro Giacca, Anna Cereseto
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253118301070

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http://www.sciencedirect.com/science/article/pii/S2162253118301070

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