The SAGA/TREX-2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally

The SAGA/TREX-2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally

Abstract Background Eukaryotic transcription is regulated through two complexes, the general transcription factor IID (TFIID) and the coactivator Spt–Ada–Gcn5 acetyltransferase (SAGA). Recent findings confirm that both TFIID and SAGA contribute to the synthesis of nearly all transcripts and are recr...

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Bibliographic Details
Main Authors: Varinia García-Molinero, José García-Martínez, Rohit Reja, Pedro Furió-Tarí, Oreto Antúnez, Vinesh Vinayachandran, Ana Conesa, B. Franklin Pugh, José E. Pérez-Ortín, Susana Rodríguez-Navarro
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Epigenetics & Chromatin
Subjects:
Sus1
SAGA
Transcription
GRO
ChIP-exo
Online Access:http://link.springer.com/article/10.1186/s13072-018-0184-2

Internet

http://link.springer.com/article/10.1186/s13072-018-0184-2

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