HDAC6 is associated with the formation of aortic dissection in human

HDAC6 is associated with the formation of aortic dissection in human

Abstract Background The pathological features of aortic dissection (AD) include vascular smooth muscle cell (VSMC) loss, elastic fiber fraction, and inflammatory responses in the aorta. However, little is known about the post-translational modification mechanisms responsible for these biological pro...

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Bibliographic Details
Main Authors: Xian Guo, Ze-Min Fang, Xiang Wei, Bo Huo, Xin Yi, Cai Cheng, Jun Chen, Xue-Hai Zhu, Anas Omar Khalil Abu Bokha, Ding-Sheng Jiang
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Molecular Medicine
Subjects:
Aortic dissection
Histone post-translational modification
HDAC6
H3K23ac
H4K20me2
Signaling pathway
Online Access:http://link.springer.com/article/10.1186/s10020-019-0080-7

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http://link.springer.com/article/10.1186/s10020-019-0080-7

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