Primary oral manifestation of Langerhans cell histiocytosis refractory to conventional therapy but susceptible to BRAF-specific treatment: a case report and review of the literature

Langerhans cell histiocytosis (LCH) is a diagnostic and therapeutic challenge. We report on a rare case of its primary oral manifestation that was treated successfully with the BRAF-specific agent, vemurafenib, after insufficient standard LCH treatment. This case underlines the importance of proper...

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Bibliographic Details
Main Authors: Norbert Neckel, Andrej Lissat, Arendt von Stackelberg, Nadine Thieme, Mohemed-Salim Doueiri, Birgit Spors, Benedicta Beck-Broichsitter, Max Heiland, Jan-Dirk Raguse
Format: Article
Language:English
Published: SAGE Publishing 2019-10-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758835919878013