Enhanced generation of human induced pluripotent stem cells by ectopic expression of Connexin 45

Abstract Somatic cells can be successfully reprogrammed into pluripotent stem cells by the ectopic expression of defined transcriptional factors. However, improved efficiency and better understanding the molecular mechanism underlying reprogramming are still required. In the present study, a scrape...

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Bibliographic Details
Main Authors: Qiong Ke, Li Li, Xin Yao, Xingqiang Lai, Bing Cai, Hong Chen, Rui Chen, Zhichen Zhai, Lihua Huang, Kai Li, Anbin Hu, Frank Fuxiang Mao, Andy Peng Xiang, Liang Tao, Weiqiang Li
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00523-y