Wogonin Prevents Glucocorticoid-Induced Thymocyte Apoptosis Without Diminishing Its Anti-inflammatory Action

The effect of wogonin, a flavone highly purified from the roots of Scutellaria baicalensis, on apoptotic cell death was re-evaluated in rat thymocytes. This flavone inhibited glucocorticoid-induced apoptotic changes such as DNA fragmentation, phosphatidylserine translocation, and nuclear condensatio...

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Bibliographic Details
Main Authors: Riyo Enomoto, Chiyoko Sugahara, Chie Suzuki, Ikumi Nagase, Yoshimi Takamura, Asa Yoshikawa, Akiko Hosoda, Hiroyuki Hirano, Toshio Yokoi, Eibai Lee
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319342343