Assessing biological and technological variability in protein levels measured in pre-diagnostic plasma samples of women with breast cancer

Abstract Background Quantitative proteomics allows for the discovery and functional investigation of blood-based pre-diagnostic biomarkers for early cancer detection. However, a major limitation of proteomic investigations in biomarker studies remains the biological and technical variability in the...

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Bibliographic Details
Main Authors: Christine Y. Yeh, Ravali Adusumilli, Majlinda Kullolli, Parag Mallick, Esther M. John, Sharon J. Pitteri
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Biomarker Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40364-017-0110-y