β-arrestin 2 quenches TLR signaling to facilitate the immune evasion of EPEC

β-arrestin 2 quenches TLR signaling to facilitate the immune evasion of EPEC

The protein translocated intimin receptor (Tir) from enteropathogenic Escherichia coli shares sequence similarity with the host cellular immunoreceptor tyrosine-based inhibition motifs (ITIMs). The ITIMs of Tir are required for Tir-mediated immune inhibition and evasion of host immune responses. How...

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Bibliographic Details
Main Authors: Zijuan Chen, Ruixue Zhou, Yihua Zhang, Doudou Hao, Yu Wang, Shichao Huang, Ningning Liu, Chunmei Xia, Nissan Yissachar, Feng Huang, Yiwei Chu, Dapeng Yan
Format: Article
Language:English
Published: Taylor & Francis Group 2020-09-01
Series:Gut Microbes
Subjects:
β-arrestin 2
traf6
tak1
tlr signaling
immune evasion
epec
Online Access:http://dx.doi.org/10.1080/19490976.2020.1759490

Internet

http://dx.doi.org/10.1080/19490976.2020.1759490

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