Metabolism of remimazolam in primary human hepatocytes during continuous long-term infusion in a 3-D bioreactor system

Metabolism of remimazolam in primary human hepatocytes during continuous long-term infusion in a 3-D bioreactor system

Nora Freyer,1 Fanny Knöspel,1 Georg Damm,2 Selina Greuel,1 Christin Schneider,1 Daniel Seehofer,2 Thomas Stöhr,3 Karl-Uwe Petersen,3 Katrin Zeilinger1 1Berlin Brandenburg Center for Regenerative Therapies (BCRT), Charité – Universitätsmedizin Berlin,...

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Bibliographic Details
Main Authors: Freyer N, Knöspel F, Damm G, Greuel S, Schneider C, Seehofer D, Stöhr T, Petersen KU, Zeilinger K
Format: Article
Language:English
Published: Dove Medical Press 2019-04-01
Series:Drug Design, Development and Therapy
Subjects:
benzodiazepine
metabolite
CNS7054
carboxylesterase 1
steady-state
Online Access:https://www.dovepress.com/metabolism-of-remimazolam-in-primary-human-hepatocytes-during-continuo-peer-reviewed-article-DDDT

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https://www.dovepress.com/metabolism-of-remimazolam-in-primary-human-hepatocytes-during-continuo-peer-reviewed-article-DDDT

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