STAT3 in Cancer—Friend or Foe?

The roles and significance of STAT3 in cancer biology have been extensively studied for more than a decade. Mounting evidence has shown that constitutive activation of STAT3 is a frequent biochemical aberrancy in cancer cells, and this abnormality directly contributes to tumorigenesis and shapes man...

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Bibliographic Details
Main Authors: Hai-Feng Zhang, Raymond Lai
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/6/3/1408