Validation of differentially methylated microRNAs identified from an epigenome-wide association study; Sanger and next generation sequencing approaches

Validation of differentially methylated microRNAs identified from an epigenome-wide association study; Sanger and next generation sequencing approaches

Abstract Objectives Altered DNA methylation and microRNA profiles are associated with diabetic kidney disease. This study compared different sequencing approaches to define the genetic and epigenetic architecture of sequences surrounding microRNAs associated with diabetic kidney disease. Results We...

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Bibliographic Details
Main Authors: Laura J. Smyth, Alexander P. Maxwell, Katherine A. Benson, Jill Kilner, Gareth J. McKay, Amy Jayne McKnight
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Research Notes
Subjects:
Diabetes
Epigenetic
EWAS
Kidney
Methylation
microRNA
Online Access:http://link.springer.com/article/10.1186/s13104-018-3872-x

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http://link.springer.com/article/10.1186/s13104-018-3872-x

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