Alterations in Glutathione Redox Metabolism, Oxidative Stress, and Mitochondrial Function in the Left Ventricle of Elderly Zucker Diabetic Fatty Rat Heart

Alterations in Glutathione Redox Metabolism, Oxidative Stress, and Mitochondrial Function in the Left Ventricle of Elderly Zucker Diabetic Fatty Rat Heart

The Zucker diabetic fatty (ZDF) rat is a genetic model in which the homozygous (FA/FA) male animals develop obesity and type 2 diabetes. Morbidity and mortality from cardiovascular complications, due to increased oxidative stress and inflammatory signals, are the hallmarks of type 2 diabetes. The pr...

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Bibliographic Details
Main Authors: Haider Raza, Annie John, Frank C. Howarth
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:International Journal of Molecular Sciences
Subjects:
Zucker rats
diabetes
obesity
oxidative stress
cardiomyocytes
mitochondria
Online Access:http://www.mdpi.com/1422-0067/13/12/16241

Internet

http://www.mdpi.com/1422-0067/13/12/16241

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