Micelles of Progesterone for Topical Eye Administration: Interspecies and Intertissues Differences in Ex Vivo Ocular Permeability

Micelles of Progesterone for Topical Eye Administration: Interspecies and Intertissues Differences in Ex Vivo Ocular Permeability

Progesterone (PG) may provide protection to the retina during retinitis pigmentosa, but its topical ocular supply is hampered by PG poor aqueous solubility and low ocular bioavailability. The development of efficient topical ocular forms must face up to two relevant challenges: Protective barriers o...

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Bibliographic Details
Main Authors: Adrián M. Alambiaga-Caravaca, María Aracely Calatayud-Pascual, Vicent Rodilla, Angel Concheiro, Alicia López-Castellano, Carmen Alvarez-Lorenzo
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceutics
Subjects:
progesterone
retinitis pigmentosa
interspecies ocular permeability differences
polymeric micelles
Soluplus
Pluronic
Online Access:https://www.mdpi.com/1999-4923/12/8/702

Internet

https://www.mdpi.com/1999-4923/12/8/702

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