Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in hepatocellular carcinoma development.

BACKGROUND: The biological pathways and functional properties by which misexpressed microRNAs (miRNAs) contribute to liver carcinogenesis have been intensively investigated. However, little is known about the upstream mechanisms that deregulate miRNA expressions in this process. In hepatocellular ca...

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Bibliographic Details
Main Authors: Wing-Kit Yip, Alfred Sze-Lok Cheng, Ranxu Zhu, Raymond Wai-Ming Lung, Daisy Pui-Fong Tsang, Suki Shuk-Kei Lau, Yangchao Chen, Jonathan Gabriel Sung, Paul Bo-San Lai, Enders Kai-On Ng, Jun Yu, Nathalie Wong, Ka-Fai To, Vincent Wai-Sun Wong, Joseph Jao-Yiu Sung, Henry Lik-Yuen Chan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3150371?pdf=render