Dendritic Cells From the Cervical Mucosa Capture and Transfer HIV-1 via Siglec-1

Dendritic Cells From the Cervical Mucosa Capture and Transfer HIV-1 via Siglec-1

Antigen presenting cells from the cervical mucosa are thought to amplify incoming HIV-1 and spread infection systemically without being productively infected. Yet, the molecular mechanism at the cervical mucosa underlying this viral transmission pathway remains unknown. Here we identified a subset o...

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Bibliographic Details
Main Authors: Daniel Perez-Zsolt, Jon Cantero-Pérez, Itziar Erkizia, Susana Benet, Maria Pino, Carla Serra-Peinado, Alba Hernández-Gallego, Josep Castellví, Gustavo Tapia, Vicent Arnau-Saz, Julio Garrido, Antoni Tarrats, Maria J. Buzón, Javier Martinez-Picado, Nuria Izquierdo-Useros, Meritxell Genescà
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
cervix
Siglec-1
HIV-1
trans-infection
myeloid cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00825/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00825/full

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