Modifying Intestinal Integrity and MicroBiome in Severe Malnutrition with Legume-Based Feeds (MIMBLE 2.0): protocol for a phase II refined feed and intervention trial [version 1; referees: 2 approved]

Modifying Intestinal Integrity and MicroBiome in Severe Malnutrition with Legume-Based Feeds (MIMBLE 2.0): protocol for a phase II refined feed and intervention trial [version 1; referees: 2 approved]

Background: Changes in intestinal mucosal integrity and gut microbial balance occur in severe acute malnutrition (SAM), resulting in treatment failure and adverse clinical outcomes (gram-negative sepsis, diarrhoea and high case-fatality). Transient lactose intolerance, due to loss of intestinal brus...

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Bibliographic Details
Main Authors: Kevin Walsh, Nuala Calder, Peter Olupot-Olupot, Tonny Ssenyondo, William Okiror, Charles Bernard Okalebo, Rita Muhindo, Ayub Mpoya, Elaine Holmes, Julian Marchesi, Gael Delamare de la Villenaise de Chenevarin, Gary Frost, Kathryn Maitland
Format: Article
Language:English
Published: Wellcome 2018-08-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/3-95/v1

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https://wellcomeopenresearch.org/articles/3-95/v1

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