T-type Ca2+ channel enhancer SAK3 administration improves the BPSD-like behaviors in AppNL−G-F/NL−G-F knock-in mice

Alzheimer's disease (AD) accounts for the majority of dementia among the elderly. In addition to cognitive impairment, behavioral and psychological symptoms (BPSD) such as depression tendency and increased aggression impose a great burden on the patient. However, there is still no rational ther...

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Bibliographic Details
Main Authors: Tomohide Degawa, Ichiro Kawahata, Hisanao Izumi, Yasuharu Shinoda, Kohji Fukunaga
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000189