EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration

Abstract Age-related macular degeneration (AMD) is a highly prevalent degenerative disease and a leading cause of vision loss worldwide. Evidence for an inflammatory component in the development of AMD exists, yet the exact mechanisms remain unclear. Bisretinoid N-retinylidene-N-retinylethanolamine...

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Bibliographic Details
Main Authors: Jon Ambæk Durhuus, Maarten P. Rozing, Marie Krogh Nielsen, Christopher Rue Molbech, Guido Keijzers, Morten Scheibye-Knudsen, Lene Juel Rasmussen, Rudi G. J. Westendorp, Torben Lykke Sørensen
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87337-1