Thiopurine S-methyltransferase polymorphisms in acute lymphoblastic leukemia, inflammatory bowel disease and autoimmune disorders: influence on treatment response
Rachid Abaji,1 Maja Krajinovic2 1Department of Pharmacology, 2Departments of Pediatrics and Pharmacology, CHU Sainte-Justine Research Center, University of Montreal, Montreal, QC, Canada Abstract: The thiopurine S-methyltransferase (TPMT) gene encodes for the TPMT enzyme that plays a crucial role in...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2017-05-01
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| Series: | Pharmacogenomics and Personalized Medicine |
| Subjects: | |
| Online Access: | https://www.dovepress.com/thiopurine-s-methyltransferase-polymorphisms-in-acute-lymphoblastic-le-peer-reviewed-article-PGPM |