The interaction between amyloid-β peptides and anionic lipid membranes containing cholesterol and melatonin.

One of the hallmarks of Alzheimer's disease is the formation of senile plaques, primarily consisting of amyloid-β (Aβ) peptides. Peptide-membrane and peptide-lipid interactions are thought to be crucial in this process. We studied the interaction of Aβ₁₋₄₂ and Aβ₂₅₋₃₅ peptides with anionic lipi...

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Bibliographic Details
Main Authors: Hannah Dies, Laura Toppozini, Maikel C Rheinstädter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24915524/?tool=EBI