Treatment with NADPH oxidase inhibitor apocynin alleviates diabetic neuropathic pain in rats

Treatment with NADPH oxidase inhibitor apocynin alleviates diabetic neuropathic pain in rats

Increased reactive oxygen species by the activation of NADPH oxidase (NOX) contributes to the development of diabetic complications. Apocynin, a NOX inhibitor, increases sciatic nerve conductance and blood flow in diabetic rats. We investigated potential protective effect of apocynin in rat diabetic...

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Bibliographic Details
Main Authors: Murat Olukman, Aytül Önal, Fatma Gül Çelenk, Yiğit Uyanıkgil, Türker Çavuşoğlu, Neslihan Düzenli, Sibel Ülker
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
apocynin; diabetic complications; experimental diabetes mellitus; neuropathic pain; NADPH oxidase; sciatic nerve; spinal cord; Western blotting; peripheral nerve injury; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=9;spage=1657;epage=1664;aulast=Olukman

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=9;spage=1657;epage=1664;aulast=Olukman

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