P53 and cancer-associated sialylated glycans are surrogate markers of cancerization of the bladder associated with Schistosoma haematobium infection.

Bladder cancer is a significant health problem in rural areas of Africa and the Middle East where Schistosoma haematobium is prevalent, supporting an association between malignant transformation and infection by this blood fluke. Nevertheless, the molecular mechanisms linking these events are poorly...

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Main Authors: Júlio Santos, Elisabete Fernandes, José Alexandre Ferreira, Luís Lima, Ana Tavares, Andreia Peixoto, Beatriz Parreira, José Manuel Correia da Costa, Paul J Brindley, Carlos Lopes, Lúcio L Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4263606?pdf=render