Genetic polymorphisms of autophagy-related gene 5 (ATG5) rs473543 predict different disease-free survivals of triple-negative breast cancer patients receiving anthracycline- and/or taxane-based adjuvant chemotherapy

Genetic polymorphisms of autophagy-related gene 5 (ATG5) rs473543 predict different disease-free survivals of triple-negative breast cancer patients receiving anthracycline- and/or taxane-based adjuvant chemotherapy

Abstract Background Autophagy plays a crucial role in chemotherapy resistance of triple-negative breast cancer (TNBC). Hence, autophagy-related gene 5 (ATG5), an essential molecule involved in autophagy regulation, is presumably associated with recurrence of TNBC. This study was aimed to investigate...

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Bibliographic Details
Main Authors: Meiying Li, Fei Ma, Jiayu Wang, Qing Li, Pin Zhang, Peng Yuan, Yang Luo, Ruigang Cai, Ying Fan, Shanshan Chen, Qiao Li, Binghe Xu
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Chinese Journal of Cancer
Subjects:
Autophagy-related gene 5
Triple-negative breast cancer
Disease-free survival
Anthracycline
Taxanes
Online Access:http://link.springer.com/article/10.1186/s40880-018-0268-1

Internet

http://link.springer.com/article/10.1186/s40880-018-0268-1

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