Co-infection with the friend retrovirus and mouse scrapie does not alter prion disease pathogenesis in susceptible mice.

Co-infection with the friend retrovirus and mouse scrapie does not alter prion disease pathogenesis in susceptible mice.

Prion diseases are fatal, transmissible neurodegenerative diseases of the central nervous system. An abnormally protease-resistant and insoluble form (PrP(Sc)) of the normally soluble protease-sensitive host prion protein (PrP(C)) is the major component of the infectious prion. During the course of...

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Bibliographic Details
Main Authors: Pascal Leblanc, Kim Hasenkrug, Anne Ward, Lara Myers, Ronald J Messer, Sandrine Alais, Andrew Timmes, Suzette A Priola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3266293?pdf=render

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http://europepmc.org/articles/PMC3266293?pdf=render

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