Galectin-1 Impairs the Generation of Anti-Parasitic Th1 Cell Responses in the Liver during Experimental Visceral Leishmaniasis

Galectin-1 Impairs the Generation of Anti-Parasitic Th1 Cell Responses in the Liver during Experimental Visceral Leishmaniasis

Many infectious diseases are characterized by the development of immunoregulatory pathways that contribute to pathogen persistence and associated disease symptoms. In diseases caused by intracellular parasites, such as visceral leishmaniasis (VL), various immune modulators have the capacity to negat...

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Bibliographic Details
Main Authors: Patrick T. Bunn, Marcela Montes de Oca, Fabian de Labastida Rivera, Rajiv Kumar, Chelsea L. Edwards, Rebecca J. Faleiro, Susanna S. Ng, Meru Sheel, Yulin Wang, Fiona H. Amante, Ashraful Haque, Christian R. Engwerda
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
Leishmania
visceral leishmaniasis
galectin-1
T cells
inflammation
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01307/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01307/full

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