Metabolic engineering of Escherichia coli for efficient production of l-alanyl-l-glutamine

Metabolic engineering of Escherichia coli for efficient production of l-alanyl-l-glutamine

Abstract Background l-Alanyl-l-glutamine (AQ) is a functional dipeptide with high water solubility, good thermal stability and high bioavailability. It is widely used in clinical treatment, post-operative rehabilitation, sports health care and other fields. AQ is mainly produced via chemical synthes...

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Bibliographic Details
Main Authors: Jiangming Zhu, Wei Yang, Bohua Wang, Qun Liu, Xiaotong Zhong, Quanxiu Gao, Jiezheng Liu, Jianzhong Huang, Baixue Lin, Yong Tao
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Microbial Cell Factories
Subjects:
AQ
Metabolic engineering
Whole-cell biocatalysis
l-amino acid α-ligase
Glutamine synthase
Online Access:http://link.springer.com/article/10.1186/s12934-020-01369-2

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http://link.springer.com/article/10.1186/s12934-020-01369-2

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