Proteomics of Muscle Microdialysates Identifies Potential Circulating Biomarkers in Facioscapulohumeral Muscular Dystrophy

Proteomics of Muscle Microdialysates Identifies Potential Circulating Biomarkers in Facioscapulohumeral Muscular Dystrophy

Facioscapulohumeral muscular dystrophy (FSHD) is caused by a complex epigenetic mechanism finally leading to the misexpression of <i>DUX4</i> in skeletal muscle. Detecting DUX4 and quantifying disease progression in FSHD is extremely challenging, thus increasing the need for surrogate bi...

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Bibliographic Details
Main Authors: Victor Corasolla Carregari, Mauro Monforte, Giuseppe Di Maio, Luisa Pieroni, Andrea Urbani, Enzo Ricci, Giorgio Tasca
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
facioscapulohumeral muscular dystrophy
FSHD
inflammatory response
proteomics
biomarkers
Online Access:https://www.mdpi.com/1422-0067/22/1/290

Internet

https://www.mdpi.com/1422-0067/22/1/290

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