BRM270 Inhibits the Proliferation of CD44 Positive Pancreatic Ductal Adenocarcinoma Cells via Downregulation of Sonic Hedgehog Signaling

BRM270 Inhibits the Proliferation of CD44 Positive Pancreatic Ductal Adenocarcinoma Cells via Downregulation of Sonic Hedgehog Signaling

Pancreatic cancer has a poor survival rate as compared to other types of cancer. Surface marker CD44 plays important role in epithelial-mesenchymal transition and cancer stem cell phenotype. Therefore, targeting CD44 positive pancreatic cancer cells might enhance therapies effectiveness. Our previou...

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Bibliographic Details
Main Authors: Do Luong Huynh, Hyebin Koh, Nisansala Chandimali, Jiao Jiao Zhang, Nameun Kim, Tae Yoon Kang, Mrinmoy Ghosh, Meeta Gera, Yang-Ho Park, Taeho Kwon, Dong Kee Jeong
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2019/8620469

Internet

http://dx.doi.org/10.1155/2019/8620469

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