The p53 isoform delta133p53ß regulates cancer cell apoptosis in a RhoB-dependent manner.

The p53 isoform delta133p53ß regulates cancer cell apoptosis in a RhoB-dependent manner.

The TP53 gene plays essential roles in cancer. Conventionally, wild type (WT) p53 is thought to prevent cancer development and metastasis formation, while mutant p53 has transforming abilities. However, clinical studies failed to establish p53 mutation status as an unequivocal predictive or prognost...

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Bibliographic Details
Main Authors: Nikola Arsic, Alexandre Ho-Pun-Cheung, Evelyne Lopez-Crapez, Eric Assenat, Marta Jarlier, Christelle Anguille, Manon Colard, Mikaël Pezet, Pierre Roux, Gilles Gadea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5315499?pdf=render

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http://europepmc.org/articles/PMC5315499?pdf=render

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