Molecular Relationships among Obesity, Inflammation and Intervertebral Disc Degeneration: Are Adipokines the Common Link?

Molecular Relationships among Obesity, Inflammation and Intervertebral Disc Degeneration: Are Adipokines the Common Link?

Intervertebral disc degeneration (IVDD) is a chronic, expensive, and high-incidence musculoskeletal disorder largely responsible for back/neck and radicular-related pain. It is characterized by progressive degenerative damage of intervertebral tissues along with metabolic alterations of all other ve...

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Bibliographic Details
Main Authors: Clara Ruiz-Fernández, Vera Francisco, Jesus Pino, Antonio Mera, Miguel Angel González-Gay, Rodolfo Gómez, Francisca Lago, Oreste Gualillo
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
adipokines
adiponectin
adipose tissue
annulus fibrosus
immune system
intervertebral disc degeneration
leptin
metabolism
nucleus pulposus
obesity
Online Access:https://www.mdpi.com/1422-0067/20/8/2030

Internet

https://www.mdpi.com/1422-0067/20/8/2030

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